Does it matter if you fish bait or artificials when the moon is full on a cloudless night?
I definitely think so, and feel the bait sitting there will work better on a cloudless night, than some artificial presentations.
I would also point out that when you have a "fire in the water" situation where phosphorescence is present, fishing bait may give some anglers an edge because I feel it looks more natural sitting in the water than the plug you're throwing that looks like it's possessed.