I don't have chafing problems with my breathables, but I ain't wearin breathables on the rocks at Montauk just to slice a hole in em when I get knocked sideways.
So it's the neoprene backup pair for me. Whenever I wear them for more than a day, my ankles get chafed by the pants and I get bloody blisters.
Here's my solution...
Might look kinda weird, but I wrap the tape loosely, circulation is fine. More importantly, I wore the waders for 2 days with no chafing, rash, I'm jumpin for joy!